Vardenafil, as well as Sildenafil are both medicines.
They are used for treating Erectile Dysfunction (ED) for males or in men who are assigned to be males when they were born (AMAB).
Erectile Dysfunction refers to the inability to maintain and achieve an unshakeable erection.
Sildenafil was the initial drug that Food and Drugs Administration (FDA) was able to approve for treating ED. However, Vardenafil was approved afterward.
Let’s look at the text to learn more about: Vardenafil vs Sildenafil and which one is the most suitable medication for you.
Basics of Sildenafil and Vardenafil
Sildenafil is, as we have mentioned is the very first FDA-approved medicine for impotence, also known as Erectile Dysfunction.
The active ingredient of Viagra and other generic Viagra medication is Sildenafil.
Look up Sildenafil medicines on Medsctrl:
However, FDA approved Vardenafil in 2003 and brought it on the market under the brand name Levitra.
Look up Vardenafil prescriptions on Medsctrl:
Sildenafil can also be used for the treatment of Pulmonary Arterial Hypertension. However, Vardenafil is only used as an Erectile Dysfunction medicine.
Vardenafil Vs Sildenafil do they function?
Sildenafil and Vardenafil are similar.
Both are part of the class that includes Phosphodiesterase kind 5 (PDE5) inhibitors.
PDE5 inhibition increases the amounts of cyclic Guanosine Monophosphate (cGMP).
The increased cGMP levels to relax the muscles of smoothness. The dilation of blood vessels that line the region of penile.
Dialation of blood vessels helps to improve blood circulation in the penile region.
The increased blood flow will assist a man AMAB to achieve an erection.
But sexual stimulation is vital in order to get an erection.
What effects last longer? Vardenafil or Sildenafil
Effects of Sildenafil and Vardenafil are dependent on the health condition of the individual.
The average half-life of Vardenafil is between 4-6 hours. As per one article on some individuals these effects Vardenafil can last for up to 8 hours.
The half-life of Sildenafil is between 3 and 5 hours.
This means that the effects be gone within three hours of taking an Sildenafil pill.
Although the differences aren’t massive, Vardenafil lasts a little longer than Sildenafil.
Which is more effective between Vardenafil and Sildenafil
The time of actions of the two Sildenafil or Vardenafil is identical.
Both medications begin to work after 30 minutes after consumption.
However, the health of an individual and other variables are also a factor in the speed at which the medicine will be effective.
If you had a high fat meal prior to consuming Sildenafil or Vardenafil, the process of onset may be delayed.
Vardenafil or Sildenafil absorption may be delayed by eating a diet high in fat.
It is therefore recommended to take these pills 30 to 60 minutes prior to having an intercourse.
Suggestion
For greater results, you should for better results, Sildenafil as well as Vardenafil with a full stomach, or following eating a light meal.
Which one has the most adverse negative side effects: Vardenafil or Sildenafil
Vardenafil and Sildenafil adverse reactions are not uncommon.
Common adverse effects include:
- Headache
- Dizziness
- Nausea
- Flushing
- Heartburn
- Stomach upset
- Back back pain
- Sleep issues
- Runny or stuffy nose
- Vision shifts
- Lightheadedness
- Heartbeat irregularity
- Breathing shortness
- Priapism
The side effects of headaches and stomach indigestion may persist even when the medication wears off.
Warnning
An erection lasting longer than four hours, and which can be painful in some instances is referred to as Priapism.
Sildenafil vs Vardenafil: A comparison
Vardenafil along with Sildenafil are quite similar, however they there are some important differentiators.
Let’s take a look at the table to discover the difference between Sildenafil and Vardenafil:
| Factors | Vardenafil | Sildenafil |
| Group | PDE5 inhibitors | PDE5 inhibitors |
| Utilized in the treatment of | Erectile Dysfunction | Erectile Dysfunction as well as Pulmonary Arterial Hypertension |
| Medicines of the brand name | Levitra | Viagra |
| Generics are available | Available | Available |
| The beginning of the an action | 30 minutes | 30 minutes |
| How long will the effects last? | The effects start to wear off approximately 4 hours after which they can be present for until 8 hours. | It usually lasts between 3 to 5 hours. |
Which is more efficient, Sildenafil or Vardenafil
Vardenafil and Sildenafil perform similarly medically.
In the course of a study in which 92% of the participants reported an improvement in their erections upon drinking Vardenafil.
An additional research about Sildenafil Citrate showed 95% of males experienced improved erections.
Thus it is evident that the two Vardenafil as well as Sildenafil are equally efficient in the treatment of Erectile Dysfunction in males.
They both boost supply of blood into the penile area and this aids in getting an erection.
The time for the onset of action for both drugs takes about 30 minutes.
Which one is superior, Vardenafil or Sildenafil?
Sildenafil and Vardenafil both are recognized as powerful treatments for ED.
Vardenafil is more effective than Sildenafil.
But both medicines are effective within 30 minutes , and both cause the same adverse consequences.
Generics for both medicines are available and are less expensive than brand name medicines.
Thus, Vardenafil has a little advantage over us.
But, before taking any medicine you are prescribed, talk to your physician first.
FAQ’s
Does Vardenafil last longer than Sildenafil?
In general those effects caused by Vardenafil are lasting between 4 and 6 hours. The effects of Sildenafil’s extend for up to 3 to 5 hours.
How long will it take to get Vardenafil to start working?
Vardenafil is a drug that requires minimum 30 minutes to be absorbed before showing its effects.
However, it’s also contingent on an individual’s health as well as other aspects. So, it is recommended to take this medication 30 to 60 minutes prior to sexual exercise.
How long will it take to get Sildenafil working?
Sildenafil generally begins working in about 30 mins. But, based on variables such as the intake of fat-rich food items and the health of an individual it could last up to an hour.
